Mast cell quantification in the skin of dogs with hormonal dermatosis

Autores

  • Glícia Meneses Costa Universidade Estadual do Ceará, Fortaleza-CE, Brasil.
  • Steffi Lima Araujo Universidade Estadual do Ceará, Fortaleza-CE, Brasil.
  • Francisco Antônio Félix Xavier Júnior Universidade Estadual do Ceará, Fortaleza-CE, Brasil.
  • Glayciane Bezerra de Morais Universidade Estadual do Ceará, Fortaleza-CE, Brasil.
  • João Alison de Moraes Silveira Universidade Estadual do Ceará, Fortaleza-CE, Brasil.
  • Daniel Araujo Viana PATHOVET, Anatomia Patológica e Patologia Clínica Veterinária, Fortaleza-CE, Brasil.
  • Janaina Serra Azul Monteiro Evangelista Universidade Estadual do Ceará, Fortaleza-CE, Brasil.

DOI:

https://doi.org/10.26605/medvet-v13n3-3314

Palavras-chave:

hypothyroidism, hyperadrenocorticism, endocrinopathies.

Resumo

The mast cells are important in physiological and pathological skin events. They play an important role in the homeostatic regulatory mechanisms in the skin and thyroid gland. Mast cells present a barrier to difference external environmental stimuli and play a mediating role in the presence of infectious agents under the epidermis. This study aimed to quantify the number of mast cells in histological sections of the skin of healthy dogs and dogs with hypothyroidism and hyperadrenocorticism and to determine the distribution of mast cell numbers in the superficial dermis and deep dermis.  When we compared the total mast cell count per high power field in dogs with hypothyroidism, hyperadrenocorticism and healthy dogs, only dogs with hypothyroidism had a significant difference in the quantification of mast cells per high power field, (p < 0.05). After analyzing our results, it was possible to conclude that animals with hypothyroidism produce greater amount of mast cells in the superficial dermis than patients with hyperadrenocorticism and healthy animals.

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Publicado

23-04-2020

Como Citar

Costa, G. M., Araujo, S. L., Xavier Júnior, F. A. F., Morais, G. B. de, Silveira, J. A. de M., Viana, D. A., & Evangelista, J. S. A. M. (2020). Mast cell quantification in the skin of dogs with hormonal dermatosis. Medicina Veterinária, 13(3), 375–380. https://doi.org/10.26605/medvet-v13n3-3314

Edição

v. 13 n. 3 (2019)

Seção

Clínica e cirurgia de pequenos animais

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