Maternal brachycephaly only does not influence umbilical artery resistance in late canine pregnancy

Autores

  • Vitória Nayreli Freyre Gonçalves Sandes Department of Veterinary Medicine, Federal University of Alagoas, Viçosa-AL, Brazil
  • Ligia Buzzá Roo de Mendonça Faculty of Veterinary Medicine, CESMAC University Centre, Maceió-AL, Brazil. Veterinary Diagnostic Centre (CENTROVET), Maceió-AL, Brazil
  • Diogo Ribeiro Câmara Department of Veterinary Medicine, Federal University of Alagoas, Viçosa-AL, Brazil

DOI:

https://doi.org/10.26605/medvet-v15n2-4400

Palavras-chave:

foetal Doppler, umbilical cord, resistive index, brachycephalic dogs

Resumo

The popularity of canine brachycephalic breeds is rising in many countries of the world. Brachycephalic dogs are predisposed to developing brachycephalic obstructive airway syndrome (BOAS), resulting in lower partial pressure of oxygen in the arterial blood which might influence foetal haemodynamic parameters. Therefore, this study aimed to evaluate the influence of the maternal morphological characteristic (brachycephaly) on the resistive index of the umbilical artery (RIUA) during late pregnancy. This was a non-randomized and cross-sectional study that included data of foetuses from 42 clinically healthy pregnant bitches. The RIUA was measured in 137 foetuses, from 68 and 69 brachycephalic and non-brachycephalic bitches, respectively, between the seventh to ninth weeks of pregnancy. Gestational age was determined by ultrasonography according to foetal biparietal diameter (BP) by measuring two to four foetuses/pregnant bitch. Female dogs with at least one foetus diagnosed with a consistent heart rate below 180 bpm were not included in the present study. There was a significant weekly decrease in the RIUA of foetuses from both brachycephalic and non-brachycephalic bitches, from the seventh until the last week of evaluation. No differences were detected in the RIUA ate the same gestational week between foetuses from brachycephalic and non-brachycephalic bitches. In conclusion, maternal brachycephaly only is not able to induces RIUA changes in canine foetuses during late pregnancy.

Downloads

Não há dados estatísticos.

Referências

Batista, P.R.; Gobello, C.; Rube, A.; Barrena, J.P.; Re, N.E.; Blanco, P.G. Reference range of gestational uterine artery resistance index in small canine breeds. Theriogenology, 114(1): 81-84, 2018.

Beccaglia, M.; Luvoni, G.C. Prediction of parturition in dogs and cats: accuracy at different gestational ages. Reproduction in Domestic Animals, 47(Suppl.6): 194-196, 2012.

Beccaglia, M.; Alonge, S.; Trovo, C.; Luvoni, G.C. Determination of gestational time and prediction of parturition in dogs and cats. Reproduction in Domestic Animals, 51(1): 12-17, 2016.

Bergstrom, A.; Nodtvedt, A.; Lagerstedt, A.S.; Egenvall, A.A. Incidence and breed prediction or dystocia and risk factors for cesarian section in a Swedish population of insured dogs. Veterinary Surgery, 35(8): 786-791, 2006.

Blanco, P.G.; Arias, D.O.; Gobello, C. Doppler ultrasound in canine pregnancy. Journal of Ultrasound in Medicine, 27(12):1745-1750, 2008.

Blanco, P.G; Tórtora, M.; Rodríguez, R.; Arias, D.O.; Gobello, C. Ultrasonographic assessment of maternal cardiac function and peripheral circulation during normal gestation in dogs. The Veterinary Journal, 190(1): 154-159, 2011a.

Blanco, P.G.; Rodriguez, R.; Rube, A.; Arias, D.O.; Tórtora, M.; Díaz, J.D.; Gobello, C. Doppler ultrasonographic assessment of maternal and fetal blood flow in abnormal canine pregnancy. Animal Reproduction Science, 126: 130-135, 2011b.

Blanco, P.G.; Batista, P.R.; Gómez, F.E.; Arias, D.O.; Gobello, C. Echocardiographic and Doppler assessment of maternal cardiovascular function in normal and abnormal canine pregnancies. Theriogenology, 78(6):1235-1242, 2012.

Browne, V.A.; Julian, C.G.; Toledo-Jaldin, L.; Cioffi-Ragan, D.; Vargas, E.; Moore, L.G. Uterine artery blood flow, fetal hypoxia and fetal growth. Philosophical Transactions of the Royal Society B, 370: 20140068, 2015.

Canola, R.A.M.; Sousa, M.G.; Braz, J.B.; Restan, W.A.Z.; Yamada, D.I.; Silva Filho, J.C.; Camacho, A.A. Cardiorespiratory evaluation of brachycephalic syndrome in dogs. Pesquisa Veterinária Brasileira, 38(6): 1130-1136, 2018.

Di Salvo, P.; Bocci, F.; Zelli, R.; Polisca, A. Doppler evaluation of maternal and fetal vessels during normal gestation in the bitch. Research in Veterinary Science, 81: 382-388, 2006.

Di Renzo, G.C.; Luzi, G.; Cucchia, G.C.; Caserta, G.; Fusaro, P.; Perdikaris, A.; Cosmi, E.V. The role of Doppler technology in the evaluation of fetal hypoxia. Early Human Development, 29: 259-267, 1992.

Evans, K.M.; Adams, V.J. Proportion of litters of purebred dogs born by caesarean section. Journal of Small Animal Practice, 51: 113-118, 2010.

Fawcett, A.; Barrs, V.; Awad, M.; Child, G.; Brunel, L.; Mooney, E.; Martinez-Taboada, F.; McDonald, B.; McGreevy, P. Consequences and management of canine brachycephaly in veterinary practice: perspectives from Australian veterinarians and veterinary specialists. Animals, 9(1): 1-25, 2019.

Feliciano, M.A.R.; Nepomuceno, A.C.; Cardilli, D.J.; Coutinho, L.N.; Oliveira, M.E.F.; Kirnew, M.D.; Almeida, V.T.; Vicente, W.R.R. Triplex Doppler ultrasonography in prenatal of pregnant bitches. Acta Scientiae Veterinariae, 42: 1172, 2014.

Freitas, L.A.; Mota, G.L.; Silva, H.V.R.; Silva, L.D.M. Two-dimensional sonographic and Doppler changes in the uteri of bitches according to breed, estrus cycle phase, parity, and fertility. Theriogenology, 95: 171-177, 2017.

Giannico, A.T.; Gil, E.M.U.; Garcia, D.A.A.; Froes, T.R. The use of Doppler evaluation of the canine umbilical artery in prediction of delivery time and fetal distress. Animal Reproduction Science, 154: 105-112, 2015.

Giannico, A.T.; Garcia, D.A.; Gil, E.M.; Sousa, M.G.; Froes, T.R. Assessment of umbilical artery flow and fetal heart rate to predict delivery time in bitches. Theriogenology, 86(7): 1654-1661, 2016.

Hoareau, G.L.; Jourdan, G.; Mellema, M.; Verwaerde, P. Evaluation of arterial blood gases and arterial blood pressures in brachycephalic dogs. Journal of Veterinary Internal Medicine, 26(4): 897-904, 2012.

Krebs, C.; Longo, L.D.; Leiser, R. Term ovine placental vasculature: comparison of sea level and high altitude conditions by corrosion cast and histomorphometry. Placenta, 18(1): 43-51, 1997.

Mantiziara, G; Luvoni, G.C. Advanced ultrasound techniques in small animal reproduction imaging. Reproduction in Domestic Animals, 55(Suppl.2):17-25, 2020.

Miranda, S.A.; Domingues, S.F.S. Conceptus ecobiometry and triplex Doppler ultrasonography of uterine and umbilical arteries for assessment of fetal viability in dogs. Theriogenology, 74(4): 608-617, 2010.

Moore, L.G. Fetal growth restriction and maternal oxygen transport during high altitude pregnancy. High Altitude Medicine and Biology, 4(2): 141-156, 2003.

Moore, L.G.; Charles, S.M.; Julian, C.G. Humans at high altitude: hypoxia and fetal growing. Respiratory Physiology and Neurobiology, 178(1): 181-190, 2011.

Murray, A.J. Oxygen delivery and fetal-placental growth: beyond a question of supply and demand? Placenta, 33: e16-e22, 2012.

Nautrup, C.P. Doppler ultrasonography of canine maternal and fetal arteries during normal gestation. Journal of Reproduction and Fertility, 112(2): 301-314, 1998.

Packer, R.M.A.; Hendricks, A.; Tivers, M.S.; Burn, C.C. Impact of facial conformation on canine health: brachycephalic obstructive airway syndrome. PLoS One, 10(10): e0137494, 2015.

Pourcelot, L. Applications cliniques de l’examen Doppler transcutané. In: Peronneau, P., ed. Velocimetrie ultrasonore Doppler. Paris: Seminaire INSERM, 1974. p. 213-240

Reshetnikova, O.S.; Burton, G.J.; Milovanov, A.P. Effects of hypobaric hypoxia on the fetoplacental unit: the morphometric diffusing capacity of the villous membrane at high altitude. American Journal of Obstetrics and Gynecology, 171(6): 1560-1565, 1994.

Smith, F.O. Guide to emergency interception during parturition in the dog and cat. Veterinary Clinics of North America: Small Animal Practice, 42(3): 489-499, 2012.

Souza, R.C.A.; Peres, R.; Sousa, M.G.; Camacho, A.A. Cardiac parameters during the estrous cycle of canine bitches. Pesquisa Veterinária Brasileira, 37(3): 295-299, 2017.

Turan, S.; Aberdeen, G.W.; Thompson, L.P. Chronic hypoxia alters maternal uterine and fetal hemodynamics in the full-term pregnant guinea pig. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 313(4): R330-R339, 2017.

Ward, J.; Mochel, J.P.; Seo, Y.J.; Sathe, S. Effects of the estrous cycle and pregnancy status on cardiovascular variables in healthy bitches. Journal of Veterinary Cardiology, 30: 57-68, 2020.

Wood, C.E.; Keller-Wood, M. Current paradigms and new perspectives on fetal hypoxia: implications for fetal brain development in late gestation. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 317(1): R1-R13, 2019.

Downloads

Publicado

2021-07-06

Edição

Seção

Reprodução Animal