Evaluation of bovine Parainfluenza type-3 virus and Influenza virus D participation in bovine respiratory disease of calves from Brazilian family farming

Authors

  • Natália Carrillo Gaeta Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo (USP)
  • Bruno Leonardo Mendonça Ribeiro Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo (USP)
  • Mario Augusto Reyes Alemán Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo (USP)
  • Luciano Matsumiya Thomazelli Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo (USP)
  • Edson Luiz Durigon Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo (USP)
  • Adriana Hellmeister de Campos Nogueira Instituto Biológico de São Paulo-SP
  • Eliana de Stefano Instituto Biológico de São Paulo-SP
  • Liria Hiromi Okuda Instituto Biológico de São Paulo-SP
  • Edviges Maristela Pituco Instituto Biológico de São Paulo-SP
  • Lilian Gregory Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo (USP), São Paulo-SP

DOI:

https://doi.org/10.26605/medvet-n4-1947

Keywords:

viruses, pneumonia, bovine production, Real-time PCR, tracheobronchial fluid samples

Abstract

Bovine respiratory disease (BRD) is responsible for great economic losses in bovine production with major impact on family farming. Among all possible causes of bovine respiratory disease, viruses are commonly categorized as primary etiological agents. The present study aimed to identify the presence of bovine parainfluenza type 3 virus and Influenza virus D (IVD) in tracheobronchial fluid samples of healthy calves and calves showing clinical signs of bovine respiratory disease.  Samples were collected from 42 family farming farms in São Paulo State, Brazil. A total of 141 tracheobronchial fluid samples from healthy calves (n=100) and calves showing clinical signs of bovine respiratory disease (n=41) were enrolled in this study.  No sample was positive for both viruses after Real-Time PCR. Serum neutralization for bovine Parainfluenza type 3 virus (bPI-3v) was performed using 88 randomly selected serum samples and antibodies were detected in 45.45% (40/88) samples. Serum reactive samples were detected in both healthy (46.8%; 22/47) and BRD calves (43.9%; 18/41). Regarding antibody titer, numerical differences were detected between healthy (3%) and BRD calves (9%) for titers 128-512 (P > 0.05). The present research was the first that aimed to study the presence of bPI-3V and IVD in family farming herds from São Paulo State, Brazil. This research revealed that bPI-3v is circulating in the region studied and is possibly involved in some BRD cases. On the other hand, IVD was not detected.

Downloads

Download data is not yet available.

References

Allan, E.M.; Pirie, H.M.; Selman, I.E.; Snodgrass, D.R. Some characteristics of a natural infection by parainfluenza-3 virus in a group of calves. Research in Veterinary Science, 24(3): 339-346, 1978.

Autio, T.; Pohjanvirta, T.; Holopainen, R.; Rikula, U.; Pentikainen, J.; Huovilainen, A.; Rusanen, H.; Soveri, T.; Sihvonen, L.; Pelkonen, S. Etiology of respiratory diseased in non-vaccineted, non-medicated calves in rearing herds. Veterinary Microbiology, 119(2-4): 256-265, 2007.

BRASIL. Instituto Brasileiro de Geografia e Estatística. 2014. Disponível em . Acesso em: 21 ago. 2017.

Benesi, F.J.; Bertagnon, H.G.; Wachholz, L.; Leal, M.L.R.; Fernandes,W.R.; Benites, N.R.; Melville, P.A. Microbiota bacteriana e citologia da região traqueobrônquica de bezerros no período neonatal. Pesquisa Veterinária Brasileira, 33(6):700-704, 2013.

Bosch, A.A.T.M.; Biesbroek, G.; Trzcinski, K.; Sanders, E.A.M.; Bogaert, D. Viral and bacterial interactions in the upper respiratory tract. PLoS Pathogens, 9(1), e1003057, 2013.

Candeias, J.A.N.; Ribeiro, L.C. Anticorpos inibidores da hemaglutinação para o vírus parainfluenza 3 (Ha-1), em gado bovino. Revista de Saúde Pública, 2(2):180-185, 1968.

Candeias, J.A.N; Sugay, W.; Ribeiro, L.C. Isolation of Myxovirus parainfluenza 3 from cattle in the State of São Paulo, Brazil. Revista de Saude Publica, 5:207-212, 1971.

Chiapponi, C.; Faccini, S.; De Mattia, A.; Baioni, L.; Barbieri, I.; Rosignoli, C.; Nigrelli, A.; Foni, E. Detection of influenza D virus among swine and cattle, Italy. Emergence Infectious Disease, 22(2): 352-354, 2016.

Collin, E.A.; Sheng, Z.; Lang, Y.; Ma, W.; Hause, B.M.; Li, F. Cocirculation of two distinct genetic and antigenic lineages of proposed influenza D virus in cattle. Journal of Virology, 89(2): 1036-1042, 2015.

Durham, P.J.; Hassard, L.E. Prevalence of antibodies to infectious bovine rhinotra-cheitis, parainfluenza 3, bovine respiratory syncytial, and bovine viral diarrea viruses in cattle in Saskatchewan and Alberta. Canadian Veterinary Journal, 31(12): 815-820, 1990.

Ellis, J.A. Bovine parainfluenza-3 Virus. Veterinary Clinics of North America: Food Animal Practice, 26(3): 575-593, 2010.

Ducatez, M.F.; Pelletier, C.; Meyer, G. Influenza D virus in cattle, France, 2011-2014. Emergence Infectious Disease, 21(4): 368371, 2015.

Ezzi, A.; Hatami, A.; Bahshesh, M.; Shoukri, M.R.; Gharaghozloyan, M. Serological survey of bovine herpesvirus type 1 and parainfluenza type 3 in cow farms of Qazvin province based on different ages and seasons. Archives of Razi Institute, 68(1): 53-57, 2013.

Ferguson, L.; Eckard, L.; Epperson, W.B.; Long, L.-P.; Smith, D.; Huston, C.; Genova, S.; Webby, R.; Wan, X.-F. Influenza D virus infection in Mississippi beef cattle. Virology, 486: 28-34, 2015.

Filoni, C.; Catão-Dias, J.L.; Bay, G.; Durigon, E.L.; Jorge, R.S.P.; Lutz, H.; HofmannLehmann, R. First evidence of feline herpesvirus, calicivirus, parvovirus, and ehrlichia exposure in Brazilian free-ranging felids. Journal of Wildlife Disease, 42(2): 470-477, 2006.

Giangaspero, M.; Vanopdenbosch, E.; Nishikawa, H.; Tabbaa, D. Prevalence of antibodies against respiratory viruses (Parainfluenza type 3, respiratory syncytial virus, reovirus and adenovirus) in relation to productivity in Syrian Awassi sheep. Tropical Animal Health and Production, 29(2): 83-91, 1997.

Gonçalves, D.A.; Spilki, F.R.; Chiminazzo, C.; Oliveira, M.A.; Franco, A.C.; Roehe, P.M. Isolamento do vírus Parainfluenza bovino tipo 3 no Rio Grande do Sul, Brasil. Ciência Rural, 33(5): 953-956, 2003.

Griffin, D.; Chengappa, M.M.; Kuszak, J.; McVey, D.S. Bacterial pathogens of the bovine respiratory disease complex. Veterinary Clinics of North America: Food Animal Practice, 26: 381-394, 2010.

Hause; B.M.; Ducatez, M.; Collin, E.A.; Ran, Z.; Liu, R.; Sheng, Z.; Armien, A.; Kaplan, B.; Chakravarty, S. Isolation of a novel swine influenza virus from Oklahoma in 2011 which is distantly related to human influenza C viruses. PLoS Pathogen, 9(2): e1003176, 2013.

Horwood, P.F.; Gravel, J.L.; Mahony, T.J. Identification of two distinct bovine parainfluenza virus type 3 genotypes. Journal of General Virology, 89(7): 16431648, 2008.

Horwood, P.F.; Mahony, T.J. Multiplex real-time RT-PCR detection of three viruses associated with the bovine respiratory disease complex. Journal of Virology Methods, 171(2): 360363, 2011.

Ibu, M.; Salihu, E.A.; Abechi, M.A.; AbaAdulugba, E.P.; Okewu, M. Activity of bovine parainfluenza type 3 virus in cattle in north eastern Nigeria-a short communication. Journal of Veterinary Science, 6: 1-4, 2005. International Committee on Taxonomy of Viruses (ICTV). 2014. Disponível em . Acesso em: 21 ago. 2017.

Kojuri, G.A.; Hemmatzedeh, F.; Taghadosi, C. Serological survey on bovine parainfluenza type 3 in Shahrekpord district (Iran). Comparative Clinical Pathology, 20(3): 201-204, 2011.

Mitra, N.; Cernicchiaro, N.; Torres, S.; Li, F.; Hause, B.M. Metagenomic characterization of the virome associated with bovine respiratory disease in feedlot cattle identified novel viruses and suggests an etiologic role for influenza D virus. Journal of General Virology, 97(8):1771-1784, 2016. Reed, L.J.; Muench, H. A simple method of estimating fifty per cent endpoints. The American Journal of Hygiene, 27(3): 493497, 1938.

Murphy, F.A.; Gibbs, E.P.J.; Horzinck, M.C.; Studdert, M.J. Paramyxoviridae. In: ____ Veterinary virology. 1999. p.411-428.

Oem, J.-K.; Lee, E.-Y.; Lee, K.-K.; Kim, S.-H.; Lee, M.-H.; Hyun, B.-H. Molecular characterization of a Korean bovine parainfluenza virus type 3 isolate. Veterinary Microbiology, 162(1): 224-227, 2013.

Pardon, B.; de Bleecker, K.; Dewulf, J.; Callens, J.; Boyen, F.; Catry; B.; Deprez, P. Prevalence of respiratory pathogens in deseased, non-vaccinated, routinely medicated veal calves. Veterinary Record, 169(11): 278, 2011.

Resinger, R.C.; Heddleston, K.L.; Manthel, C.A. A myxovirus (SF-4 associated with shipping fever of cattle. Journal of American Veterinary Medical Association, 135(3): 147-152, 1959.

Sardi, S.I.; Campos, G.S.; Barros, S.B.; Edelweiss, G.L.; Martins, D.T. Detecção de anticorpos contra o vírus da parainfluenza bovina tipo 3 (PI-3) e o vírus da leucose bovina (vlb) in bovinos de diferentes municípios do estado da Bahia, Brasil. Revista de Ciências Médicas e Biológicas, 1(1): 62-65, 2010.

Solís-Calderón, J.J.; Segura-Correa, J.C.; AguilarRomero, F.; Segura Correa,V.M. Detection of antibodies and risk factors for infection with bovine respiratory syncytial virus and parainfluenza virus-3 in beed cattle of Yucatan, Mexico. Preventive Veterinary Medicine, 82(1-2): 102-110, 2007. Twari, K.; Cornish, C.; Gamble, B.; Thomas, D.; Sharma, R.N. Seroprevalence of bovine parainfluenza virus type 3 (bPI-3V) in ruminants from granada. Open Journal of Veterinary Medicine, 6(2): 23-27, 2016. UNITED STATES OF AMERICA. USDA. Feedlot 2001.

Part IV: Health and Health Management on U.S. Feedlots with a capacity of 1,000 or more head. In: APHIS. Fort Collins: National Animal Health Monitoring System. 2013. Disponível em: < https://www.aphis.usda.gov/animal_health/na hms/feedlot/downloads/feedlot2011/Feed11_ dr_PartIV.pdf >. Acesso em: 21 ago. 2017.

Zhu, Y.-M.; Shi, H.-F.; Gao, Y.-R.; Xin, J.-Q.; Liu, N.-H.; Xiang, W.-H.; Ren, X.-G.; Feng, J.-K.; Zhao, L.-P.; Xue, F. Isolation and genetic characterization of bovine parainfluenza virus type 3 from cattle in China. Veterinary Microbiology, 149(3-4): 446-451, 2011.

Downloads

Published

2018-05-07

How to Cite

Carrillo Gaeta, N., Leonardo Mendonça Ribeiro, B., Augusto Reyes Alemán, M., Matsumiya Thomazelli, L., Luiz Durigon, E., Hellmeister de Campos Nogueira, A., de Stefano, E., Hiromi Okuda, L., Maristela Pituco, E., & Gregory, L. (2018). Evaluation of bovine Parainfluenza type-3 virus and Influenza virus D participation in bovine respiratory disease of calves from Brazilian family farming. Medicina Veterinária, 11(4), 227–232. https://doi.org/10.26605/medvet-n4-1947

Issue

Vol. 11 No. 4 (2017)

Section

Small Animal Clinic and Surgery

License

A Revista de Medicina Veterinária permite que o autor retenha os direitos de publicação sem restrições, utilizando para tal a licença  Creative Commons CC BY-NC-SA 4.0.

De acordo com os termos seguintes:

Atribuição — Você deve dar o crédito apropriado, prover um link para a licença e indicar se mudanças foram feitas. Você deve fazê-lo em qualquer circunstância razoável, mas de nenhuma maneira que sugira que o licenciante apoia você ou o seu uso.

NãoComercial — Você não pode usar o material para fins comerciais.

CompartilhaIgual — Se você remixar, transformar, ou criar a partir do material, tem de distribuir as suas contribuições sob a mesma licença que o original.

Sem restrições adicionais — Você não pode aplicar termos jurídicos ou medidas de caráter tecnológico que restrinjam legalmente outros de fazerem algo que a licença permita.