Efficacy of antiparasitic drugs in control of gastrointestinal helminthiasis in naturally colored and white lambs from southern Brazil

Autores

  • Pablo Tavares Costa Departamento de Zootecnia, Universidade Federal de Pelotas (UFPel), Capão do Leão-RS, Brasil.
  • Rômulo Tavares Costa Departamento de Zootecnia, Universidade Federal de Pelotas (UFPel), Capão do Leão-RS, Brasil.
  • Alexsandro Bahr Kröning Departamento de Zootecnia, Universidade Federal de Pelotas (UFPel), Capão do Leão-RS, Brasil.
  • Tiago Albandes Fernandes Departamento de Zootecnia, Universidade Federal de Pelotas (UFPel), Capão do Leão-RS, Brasil.
  • Ricardo Zambarda Vaz Departamento de Zootecnia, Universidade Federal de Pelotas (UFPel), Capão do Leão-RS, Brasil.
  • Sara Patron da Motta Departamento do Instituto de Biologia, Universidade Federal de Pelotas (UFPel), Capão do Leão-RS, Brasil.
  • Gilson de Mendonça Departamento de Fisiologia, Universidade Federal de Pelotas (UFPel), Capão do Leão-RS, Brasil.
  • Pâmela Peres Farias Departamento de Zootecnia, Universidade Federal de Pelotas (UFPel), Capão do Leão-RS, Brasil.

DOI:

https://doi.org/10.26605/medvet-v13n4-3663

Palavras-chave:

efficacy, antiparasitic, drug, helminth, sheep.

Resumo

Parasitic infections and the efficiency of different drugs were evaluated considering efficacy percentages, reduction in count of eggs per gram of feces (EPG) and larval culture in 60, 30 white and 30 naturally colored Corriedale lambs. Each phenotypic group was subdivided into six groups of five animals, each of which was administered one of the active ingredients: albendazole, levamisole hydrochloride, dysophenol, nitroxynil and moxidectin, in addition to a control group, unmedicated. Helminths were considered susceptible to nitroxinil and resistant to albendazole, levamisole, moxidectin (moderately effective) and to dysophenol (insufficiently active). In the culture of larvae, levamisole, nitroxinil and moxidectin were totally efficient (100%) against Oesophagostomum spp., moxidectin was totally efficient against Trichostrongylus spp. and nitroxinil was efficient (97%) against Haemonchus spp. Evaluating the EPG means of the phenotypic groups, it was observed higher parasitic infections in white ewes (p<0.05), in pre- and post-treatment. Therefore, it was concluded that the drug nitroxinil was the only effective for the reduction of the total parasite load of both phenotypic groups, being indicated for use in the herd in question. The genus Haemonchus spp. was the most prevalent and resistant to the drug action. Naturally colored Corriedale lambs, from the herd, showed increased resistance to gastrointestinal nematode infections.

Downloads

Não há dados estatísticos.

Referências

Amarante, A.F.T.; Sales, R.O. Control of endoparasitoses of sheeps: a revision. Revista Brasileira de Higiene e Sanidade Animal, 1(2): 14-36, 2007.

Amarante, A.F.T.; Bricarello, P.A.; Rocha, R.A.; Gennari, S.M. Resistance of Santa Ines, Suffolk and Ile de France sheep to naturally acquired gastrointestinal nematode infections. Veterinary Parasitology, 120(1-2): 91-106, 2004.

Benavides, M.V.; Sonstegard, T.S.; Kemp, S.; Mugambi, J.M.; Gibson, J.P.; Baker, R.L.; Hanotte, O.; Marshall, K.; Tassell, C.V. Identification of novel loci associated with gastrointestinal parasite resistance in a Red Maasai x Dorper backcross population. PloS One, 10(4): 1-20, 2015.

BRASIL. Ministério da Agricultura, Pecuária e Abastecimento. Portaria nº 48, de 15 de maio de 1997. In: Regulamento técnico para licenciamento e/ou renovação de licença de produtos antiparasitários de uso veterinário. Seção 1: 10165. Cited: 2017 Jul. 17.

Cerqueira, M.M.O.P.; Souza, F.N.; Cunha, A.F.; Picinin, L.C.A.; Leite, M.O.; Penna, C.F.A.M.; Souza, M.R.; Fonseca, L.M. Detection of antimicrobial and anthelmintic residues in bulk tank milk from four different mesoregions of Minas Gerais State - Brazil. Arquivos Brasileiros de Medicina Veterinária e Zootecnia, 66(2): 621-625, 2014.

Cezar, A.S.; Toscan, G.; Camillo, G.; Sangioni, L.A.; Ribas, H.O.; Vogel, F.S.F. Multiple resistance of gastrointestinal nematodes to nine different drugs in a sheep flock in southern Brazil. Veterinary Parasitology, 173(1-2): 157-160, 2010.

Coles, G.C.; Bauer, C.; Borgsteede, F.H.M.; Geerts, S.; Klei, T.R.; Taylor, M.A.; Waller, P.J. World Association for the Advancement of Veterinary Parasitology (WAAVP) methods for the detection of anthelmintic resistance in nematodes of veterinary importance. Veterinary Parasitology, 44(1-2): 35-44, 1992.

Costa, P.T.; Costa, R.T.; Mendonça, G.; Vaz, R.Z. Eficácia anti-helmíntica comparativa do nitroxinil, levamisol, closantel, moxidectina e fenbendazole no controle parasitário em ovinos. Boletim de Indústria Animal, 74(1): 72-78, 2017.

Dias, A.S.; Feleti, S.V.; Carmo, H.B.; Andrade, T.A.; Matos, E.R.; Kiefer, H.G.; Camporez, C.C. Comparação da eficácia de albendazol e a associação entre abamectina e levamisole em ovinos. Scientific Electronic Archives, 8(1): 25-28, 2015.

Echevarria, F.A.M.; Borba, M.F.S.; Pinheiro, A.C.; Waller, P.J.; Hansen, J.W. The prevalence of anthelmintic resistance in nematode parasites of sheep in Southern Latin America: Brazil. Veterinary Parasitology, 62(3-4): 199-206, 1996.

Gordon, H.McL.; Whitlock, H.V. A new technique for counting nematode eggs in sheep faeces. Journal of the Council for Scientific and Industrial Research, 12(1): 50-52, 1939.

Greer, A.W. Trade-offs and benefits: implications of promoting a strong immunity to gastrointestinal parasites in sheep. Parasite Immunology, 30(2): 123-132, 2008.

Molento, M.B.; Veríssimo, C.J.; Amarante, A.T.; Van Wyk, J.A.; Chagas, A.C.S.; Araújo, J.V.; Borges, F.A. Alternativas para o controle de nematoides gastrintestinais de pequenos ruminantes. Arquivos do Instituto de Biologia, 80(2): 253-263, 2013.

Nova, L.E.V.; Costa, M.E.; Melo, P.G.C.F.; Cunha Filho, L.F.C.; Barca Júnior, F.A.; Silva, L.C.; Okano, W.; Bogado, A.L.G. Resistência de nematoides aos anti-helmínticos nitroxinil 34% e ivermectina 1% em rebanho ovino no município de São João do Ivaí, Paraná. Revista Brasileira de Higiene e Sanidade Animal, 08(1): 160-171, 2014.

Roberts, F.H.S.; O’Sullivan, P.J. Methods for egg counts and larval cultures for strongyles infesting the gastro-intestinal tract of cattle. Australian Journal of Agricultural Research, 1(1): 99-102, 1950.

Saueressig, D. Ovinos/caprinos – mais diversidade. Revista A Granja, 191: 1-1, 2015.

Schallig, H.D. Immunological responses of sheep to Haemonchus contortus. Parasitology, 120(Suppl.): 63-72, 2000.

Silva, D.G.; Pilatti, J.A.; Menezes, B.M.; Brum, L.P.; Netto, C.G.; Martins, A.A. Eficácia anti-helmíntica comparativa entre diferentes princípios ativos em ovinos jovens. Pubvet, 11(4): 356-362, 2017.

Taylor, M.A.; Coop, R.L.; Wall, R.L. Veterinary parasitology. 3rd ed. Oxford: Blackwell Publishing, 2007. 874 pp.

Van Wyk, J.A.; Stenson, M.O.; Van der Merwe, J.S.; Vorster, R.J.; Viljoen, P.G. Anthelmintic resistance in South Africa: surveys indicate an extremely serious situation in sheep and goat farming. The Onderstepoort Journal of Veterinary Research, 66(4): 273-284, 1999.

Veríssimo, C.J.; Niciura, S.C.M.; Alberti, A.L.L.; Rodrigues, C.F.C.; Barbosa, C.F.C.; Chiebao, D.P.; Cardoso, D.; da Silva, G.S.; Pereira, J.R.; Margatho, L.F.; da Costa, R.L.; Nardon, R.F.; Ueno, T.E.; Curci, V.C.; Molento, M.B. Multidrug and multispecies resistance in sheep flocks from São Paulo state, Brazil. Veterinary Parasitology, 187(1-2): 209-216, 2012.

Vieira, L.S.; Teixeira, M.; Minho, A.P.; Borba, M.F.S.; Vasconcelos, A.L.C.F.; Beviláqua, C.M.L. Doenças parasitárias de ovinos. In: Selaive, A.B.; Osório, J.C.S. Produção de ovinos no Brasil. São Paulo: Roca, 2014. p. 311-342.

Woolaston, R.R.; Piper, L.R. Selection of Merino sheep for resistance to Haemonchus contortus: genetic variation. Animal Science, 62(3): 451-460, 1996.

Wood, I.B.; Amaral, N.K.; Bairden, K.; Duncan, J.L.; Kassai, T.; Malone, J.B.; Pankavich, J.A.; Reinecke, R.K.; Slocombe, O.; Taylor, S.M. World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) second edition of guidelines for evaluating the efficacy of anthelmintics in ruminants (bovine, ovine, caprine). Veterinary Parasitology, 58(3): 181-213, 1995.

Downloads

Publicado

08-07-2020

Como Citar

Costa, P. T., Costa, R. T., Kröning, A. B., Fernandes, T. A., Vaz, R. Z., Motta, S. P. da, Mendonça, G. de, & Farias, P. P. (2020). Efficacy of antiparasitic drugs in control of gastrointestinal helminthiasis in naturally colored and white lambs from southern Brazil. Medicina Veterinária, 13(4), 544–551. https://doi.org/10.26605/medvet-v13n4-3663

Edição

Seção

Medicina Veterinária Preventiva

Artigos mais lidos pelo mesmo(s) autor(es)