Frozen section biopsy for therapeutic decision in Lhasa Apso with urothelial carcinoma
DOI:
https://doi.org/10.26605/medvet-v18n4-6407Keywords:
dog, transitional cell carcinoma, intraoperative consultation, electrochemotherapy, ultrasound, oncologyAbstract
Urinary tract neoplasms increasingly affect dogs and are often associated with the development of metastatic processes, which lead to a worsening of the clinical picture with repercussions on quality and life expectancy. Urothelial carcinoma (UC) is a common neoplasm in the bladder, which can affect adjacent regions, with a commonly progressive and infiltrative appearance. Affected animals present nonspecific clinical signs, similar to urinary tract infections. Aimed to describe the occurrence of UC in a 13-year-old Lhasa Apso patient, with a clinical history of persistent hematuria despite previous treatment with antibiotics and anti-inflammatory therapy. In addition, abdominal ultrasound reveals the presence of an irregular structure in the bladder. After the clinical-diagnostic evaluation procedures, the patient underwent partial cystectomy with intraoperative consultation. The evaluation of the fragments by frozen biopsy and conventional histopathology confirmed the presence of CUT in the region of the bladder trigone without invasion of the serosal layer, and partial cystectomy was performed with complementary electrochemotherapy (ECT) with bleomycin. An oncological segment of the patient was performed, mainly associated with ultrasound monitoring of the bladder, and to date, there is no evidence of neoplastic recurrence completing 240 days of survival or disease-free time.Downloads
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Copyright (c) 2024 Felipe Gaia de Sousa, José Antônio da Cruz Neto, Suzane Lilian Beier, Guilherme Gomes Chaves, Luciana Wanderley Myrrha, Hiasmyn Lopes, Alysson Rodrigo Lamounier, Karen Yumi Ribeiro Nakagaki
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