Grade I fibroblastic meningioma in a dog: case report
DOI:
https://doi.org/10.26605/medvet-v18n3-6501Keywords:
Encephalic neoplasms, histopathology, meningeal neoplasm, veterinary oncologyAbstract
A case of grade I fibroblastic meningioma in a 13-year-old female Poodle dog is described. The patient presented clinical signs of apathy, reluctance to climb stairs, and tonic-clonic epileptic seizure. Hematological/biochemical examination indicated mild anemia, metabolic acidosis, hypoxemia, hyperglycemia, and alanine aminotransferase (ALT) and cholesterol changes. Magnetic resonance imaging revealed a notable homogeneous post-contrast enhancement in an extra-axial region located in the fronto-parietal area of the brain, measuring 1.95cm in the ventrodorsal axis, 2.12cm in the craniocaudal direction and 1.54cm in the lateral direction. The patient underwent a craniotomy to remove the neoplastic fragment, followed by cranioplasty. Histopathological analysis confirmed the benign nature of the tumor, characterized microscopically by elongated, spindle-shaped neoplastic cells, organized in bundles with presence of a significant collagenous matrix, presenting two mitoses per high-power field. After tumor removal, due to the complexity of the surgical intervention, the patient faced severe complications that led to an unfavorable prognosis, resulting in death. In summary, the diagnosis and treatment of brain neoplasms in dogs requires a multidisciplinary approach, highlighting the importance of continued research to improve the therapeutic options available for canine patients with brain tumors.Downloads
References
Cantile, C.; Youssef, S. Nervous system. In: Maxie, M.G. (Ed.) Jubb, Kennedy and Palmer’s pathology of domestic animals. Philadelphia: Saunders Elsevier, 2016. p.251-406.
Carvalho, J.R.G.; Vasconcelos, C.H.C.; Bastos, I.P.B.; Trajano, F.L.C.; Costa, T.S.; Fernandes, J.I. Meningioma intracraniano canino: relato de caso. Revista Brasileira de Medicina Veterinária, 38: 49-53, 2016.
Chaves, R.O.; Feranti, J.P.S.; Copat, B.; Ripplinger, A.; França, R.T.; Kommers, G.D.; Fighera, R.A.; Mazzanti, A. Neoplasias encefálicas em 40 cães: aspectos clínico-epidemiológicos e patológicos. Pesquisa Veterinária Brasileira, 38(4): 734-740, 2018.
Costa, R.C. Neoplasias intracranianas, espinhais e de nervos periféricos. In: Daleck, C.R.; Nardi, A.B. (Eds.) Oncologia em cães e gatos. São Paulo: Roca, 2016. p.864-907.
Dewey, C.W. Encephalopathies. In: Dewey, C.W.; Costa, R.C.D. (Eds.) Practical guide to canine and feline neurology. Iowa: John Wiley & Sons, Inc. 2015. p.141-236.
Forward, A.K.; Volk, H.A.; Decker, S.D. Postoperative survival and early complications after intracranial surgery in dogs. Veterinary Surgery, 47(4): 549-554, 2018.
Hicks, J.; Platt, S.; Kent, M.; Haley, A. Canine brain tumors: a model for the human disease? Veterinary and Comparative Oncology, 15(1): 252-272, 2017.
Higgins, R.J.; Bollen, A.W.; Dickinson, P.J.; Sisó-Llonch, S. Tumors of the Nervous System. In: Meuten, D.J. (Ed.) Tumors in domestic animals. Iowa: John Wiley & Sons, 2017. p.834-891.
Hu, H.; Barker, A.; Harcourt-Brown, T.; Jeffery, N. Systematic review of brain tumor treatment in dogs. Journal of Veterinary Internal Medicine, 29(6): 1456-1463, 2015.
Keyerleber, M.A.; McEntee, M.C.; Farrelly, J.; Thompson, M.S.; Scrivani, P.V.; Dewey, C.W. Three-dimensional conformal radiation therapy alone or in combination with surgery for treatment of canine intracranial meningiomas. Veterinary and Comparative Oncology, 13(4): 385-397, 2015.
Lopes, M.B.S.; Vandenberg, S.R. Tumor of the central nervous system. In: Fletcher, C.D.M. (Ed.) Diagnostic histopathology of tumors. Philadelphia: Saunders Elsevier, 2013. p.1933-2013.
Marcasso, R.A.; Moreira, J.R.; Valentim, L.G.; Arias, M.V.B.; Bracarense, A.P.F.R.L.M. Meningiomas em cães: Aspectos clínicos, histopatológicos e imuno-histoquímicos. Pesquisa Veterinária Brasileira, 35(10): 844-852, 2015.
Miller, A.D.; Miller, C.R.; Rossmeisl, J.H. Canine primary intracranial cancer: A clinicopathologic and comparative review of glioma, meningioma, and choroid plexus tumors. Frontiers in Oncology, 9: 1151, 2019.
Monteiro, S.R.M.; Rossmeisl, J.H.; Russell, J.; Holmes, M.A.; Wessmann, A.; Morris, J.; Dobson, J.M.; Vanhaesebrouck, A.E. Effect of radiotherapy on freedom from seizures in dogs with brain tumors. Journal of Veterinary Internal Medicine, 34(2): 821-827, 2020.
Montoliu, P.; Añor, S.; Vidal, E.; Pumarola, M. Histological and immunohistochemical study of 30 cases of canine meningioma. Journal of Comparative Pathology, 135(4): 200-207, 2006.
Patnaik, A.K.; Kay, W.J.; Hurvaitz, A.I. Intracranial meningioma: a comparative pathologic study of 28 dogs. Veterinary Pathology, 23: 369-373, 1986.
Pereira, L.B.S.B.; Pessoa, H.F.; Sousa, G.P.; Fonsêca Filho, L.B.; Bessa, A.L.G.; Albuquerque, P.V.; Alcantara, S.F.; Nascimento, J.C.S.; Amorim, M.J.A.A.L. Meningioma canino: relato de caso. PUBVET, 12(2): 1-4, 2018.
Rossmeisl, J.H.; Pancotto, T.E. Tumors of the nervous system. In: Vail, D.M.; Thamm, D.H.; Liptak, J.M. (Eds.) Withrow & MacEwen’s small animal clinical oncology. Missouri: Elsevier, 2019. p.657-674.
Silva, P.D.G.; Nardotto, J.R.B.; Filgueiras, R.R.; Mortari, A.C. Neoplasias intracranianas primárias em cães. Revista Científica de Medicina Veterinária, 12(40): 182-188, 2014.
Sessums, K.; Mariani, C. Intracranial meningioma in dogs and cats: a comparative review. Compendium, 31(7): 330-339, 2009.
Song, R.B.; Vite, C.H.; Bradley, C.W.; Cross, J.R. Postmortem evaluation of 435 cases of intracranial neoplasia in dogs and relationship of neoplasm with breed, age, and body weight. Journal of Veterinary Internal Medicine, 27(5): 1143-1152, 2013.
Summers, B.A.; Cummings, J.F.; De Lahunta, A. Tumors of the central nervous system. In: Summers, B.A.; Cummings, J.F.; De Lahunta, A. (Eds.) Veterinary neuropathology. Missouri: Mosby, 1995. p.351-401.
Suñol, A.; Mascort, J.; Font, C.; Bastante, A.R.; Pumarola, M.; Feliu-Pascual, A.L. Long-term follow-up of surgical resection alone for primary intracranial rostrotentorial tumors in dogs: 29 cases (2002-2013). Open Veterinary Journal, 7(4): 375-383, 2017.
Zamboni, R.; Alberti, T.S.; Schied, H.V.; Bermann, C.S.; Brunner, C.B.; Venancio, F.R.; Arantes, E.M.J.; Sallis, E.S.V.; Raffi, M.B. Meningioma microcístico com metástase pulmonar em canino: relato de caso. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 72(3): 794-798, 2020.
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