Erisipela suína: uma revisão

Autores

DOI:

https://doi.org/10.26605/medvet-v17n4-5563

Palavras-chave:

bactéria, epidemiologia, Erysipelothrix rhusiopathiae, suíno

Resumo

O gênero Erysipelothrix é responsável por processos patológicos em animais e humanos. Durante várias décadas, a espécie Erysipelothrix rhusiopathiae foi o único membro descrito no gênero Erysipelothrix. Atualmente, oito espécies e 28 sorotipos (1,2-26-N) estão caracterizados. Os sorotipos 1 e 2 representam mais de 80% dos isolados de E. rhusiopathiae, sendo associados à erisipela suína. A enfermidade tem sido controlada por vacinação, mas registros de casos clínicos têm causado preocupações sobre o ressurgimento da doença em países com produções relevantes de suínos. Esta revisão apresenta uma abordagem geral sobre a erisipela suína e discute os aspectos etiológicos, epidemiológicos, fatores de virulência, patogenia, diagnóstico, prevenção e controle bem como as implicações em saúde pública.

Downloads

Não há dados estatísticos.

Referências

Bang, B.H. et al. Erysipelothrix larvae sp. nov., isolated from the larval gut of the rhinoceros beetle, Trypoxylus dichotomus (Coleoptera: Scarabaeidae). Antonie van Leeuwenhoek, 107(2): 443-451, 2015.

BRASIL. Ministério da Agricultura Pecuária e Abastecimento. Instrução Normativa Nº 50 , de 24 de setembro de 2013. Disponível em: <https://www.gov.br/agricultura/pt-br/assuntos/sanidade-animal-e-vegetal/saude-animal/arquivos-das-publicacoes-de-saude-animal/IN502013.pdf>. Acesso em 06 nov.2023.

Bender, J.S. et al. Comparison of Conventional Direct and Enrichment Culture Methods for Erysipelothrix spp. from Experimentally and Naturally Infected Swine. Journal of Veterinary Diagnostic Investigation, 21(6): 863-868, 2009.

Bender, J.S. et al. Erysipelothrix spp. genotypes, serotypes, and surface protective antigen types associated with abattoir condemnations, Journal of Veterinary Diagnostic Investigation, 23(1): 139-142, 2011.

Bläckberg, A.; Trell, K.; Rasmussen, M. Erysipelas, a large retrospective study of aetiology and clinical presentation. BMC Infectious Diseases, 15: 402, 2015.

Brooke, C.J.; Riley, T.V. Erysipelothrix rhusiopathiae: bacteriology, epidemiology and clinical manifestations of an occupational pathogen. Journal of Medical Microbiology, 48(9): 789-799, 1999.

Ceccolini, M.E. et al. Systemic Erysipelothrix rhusiopathiae in seven free-ranging delphinids stranded in England and Wales. Diseases of Aquatic Organisms, 145: 173-184, 2021.

Chan, J.C. Erysipelothrix Infections. In: Balows A., Hausler W.J., Ohashi M., Turano A., Lennete E.H. Laboratory Diagnosis of Infectious Diseases. New York: Springer, 1988. p. 232-236.

Chirico, J. et al. The poultry red mite, Dermanyssus gallinae, a potential vector of Erysipelothrix rhusiopathiae causing erysipelas in hens. Medical and Veterinary Entomology, 17(2): 232-234, 2003.

Chuma, T. et al. Antimicrobial susceptibility of Erysipelothrix rhusiopathiae isolated from pigs in Southern Japan with a modified agar dilution method. The Journal of veterinary medicine science, 72(5): 643-645, 2010.

Conklin, R. H.; Steele, J. H. Erysipelothrix infections. In: Steele, J. H. CRC Handbook Series in Zoonoses. Florida: CRC Press Boca Ráton, 1979. p. 327-337.

Coutinho, T. A. et al. Phenotypic and molecular characterization of recent and archived Erysipelothrix spp. isolated from Brazilian swine. Diagnostic Microbiology and Infectious Disease, 69(2): 123-129, 2011.

Ding, Y. et al. Virulence determinants, antimicrobial susceptibility, and molecular profiles of Erysipelothrix rhusiopathiae strains isolated from China Emerging microbes and infections, 4: e69, 2015.

Eamens, G.J. et al. Evaluation of Erysipelothrix rhusiopathiae vaccines in pigs by intradermal challenge and immune responses, Veterinary Microbiology, 16(1-3): 138-148, 2006.

Eriksson, H. et al. Characterization of Erysipelothix rhusiopathiae isolates from poultry pigs, emus, the poultry red mite and other animals. Veterinary Microbiology, 137(1-2): 98-104, 2009.

Fidalgo, S.G. et al. Susceptibility of Erysipelothrix rhusiopathiae to antimicrobial agents and home disinfectants, Pathology, 34(5): 462-665, 2002.

Forde, T.L. et al. Genomic and immunogenic protein diversity of Erysipelothrix rhusiopathiae isolated from pigs in Great Britain: implications for vaccine protection. Frontiers in Microbiology, 11: 418, 2020.

Franz, B. et al. Localization of viable bacteria and bacterial antigens in arthritic joints of Erysipelothrix rhusiopathiae-infected pigs. FEMS Immunology and Medical microbiology, 12(2): 137-142, 1995.

Galán, J.E.; Timoney, J.F. Cloning and expression in Escherichia coli of a protective antigen of Erysipelothrix rhusiopathiae. Infection and Immunity, 58(9): 3116-3121, 1990.

Giménez-Lirola, L.G. et al. Improving ante mortem diagnosis of Erysipelothrix rhusiopathiae infection by use of oral fluids for bacterial, nucleic acid, and antibody detection. Journal of Microbiological Methods, 92(2): 113-121, 2013.

Grieco, M.H.; Sheldon, C. Erysipelothrix rhusiopathiae. Annals of the New York Academy of Sciences, 174 (2): 523-532, 1970.

Haesebrouck, F. et al. Efficacy of vaccines against bacterial diseases in swine: what can we expect? Veterinary Microbiology, 100 (3-4): 255-268, 2004.

Harada, K. et al. Comparison of three DNA extraction methods for detection of Erysipelothrix rhusiopathiae in chicken blood by polymerase chain reaction. Journal of veterinary diagnostic investigation, 21(3): 354-358, 2009.

Harada, T. et al. Erysipelothrix rhusiopathiae exploits cytokeratin 18-positive epithelial cells of porcine tonsillar crypts as an invasion gateway. Veterinary immunology and immunopathology, 153(3-4): 260-266, 2013.

Harada, T. et al. Phosphorylcholine and SpaA, a choline-binding protein, are involved in the adherence of Erysipelothrix rhusiopathiae to porcine endothelial cells, but this adherence is not mediated by the PAF receptor. Veterinary Microbiology, 172(1-2): 216-222, 2014.

Harrington Jr, R.; Hulse, D.C. Comparison of Two Plating Media for the Isolation of Erysipelothrix rhusiopathiae from Enrichment Broth Culture. Applied Microbiology, 22(1): 141-142, 1971.

Harrington Jr, R. et al. Comparison of a fluorescent antibody technique and cultural method for the detection of Erysipelothrix rhusiopathiae in primary broth cultures. American Journal of Veterinary Research, 35(3): 461-461, 1974.

Hoffmann, C. W.; Bilkei, G. Case Study: Chronic Erysipelas of the Sow – a Subclinical Manifestation of Reproductive Problems. Reproduction in Domestic Animals, 37(2): 119-120, 2002.

Imada, Y. et al. Serotyping of 800 strains of Erysipelothrix isolated from pigs affected with erysipelas and discrimination of attenuated live vaccine strain by genotyping. Journal of Clinical Microbiology, 42(5): 21212126. 2004.

Ingebritson, A.L. et al. Erysipelothrix rhusiopathiae: Association of Spa-type with serotype and role in protective immunity, Vaccine, 28(13): 2490-2496, 2010.

Koch, R. Untersuchungen über die Ätiologie der Wundinfektionskrankheiten. In: Schwalbe, J. Gesammelte Werke von Robert Koch. Leipzig: Robert Koch-Institut, 1878, p. 61-108.

Kucsera, G. Proposal for Standardization of the Designations Used for Serotypes of Erysipelothrix rhusiopathiae (Migula) Buchanan. International Journal of Systematic Bacteriology, 23(2): 184-188, 1973.

Löffler, F.A. Experimentelle Untersuchung über Schweinerotlauf. Arbeiten Aus Der Kaiserlichen Gesundheitsamte, 1: 46-55, 1886.

Loveday, R.K. Acute swine erysipelas in suckling pigs. Journal of the South African Veterinary Medical Association, 33(1): 3-5, 1962.

Makino, S. et al. Properties of repeat domain found in a novel protective antigen, SpaA, of Erysipelothrix rhusiopathiae. Microbial Pathogenesis, 25(2): 101-109, 1998.

Morimoto, M. et al. The Swine Erysipelas Vaccine SER-ME Effectively Protects Pigs against Challenge with the Erysipelothrix rhusiopathiae M203/I257 SpaA-Type Variant. Veterinary Sciences, 9 (382): 1-8, 2022.

McLauchlin, J.; Jones, D. Erysipelothrix and Listeria. In: Collier, L. Topley and Wilson’s Microbiology and Microbial Infections, 7th ed. London: Arnold, 1998. p. 683-708.

McNeil, M. et al. Serotypes and Spa types of Erysipelothrix rhusiopathiae isolates from British pigs (1987 to 2015). Veterinary Journal, 225: 1315, 2017.

Müller, H.E.; Krasemann, C [Immunity against Erysipelothrix rhusiopathiae infection by means of active immunization using homologous neuraminidase (author's transl)], Zeitschrift fu?r Immunita?tsforschung, experimentelle und klinische Immunologie, 151(3): 237-241, 1976.

Nassar, I.M. et al. Mitro-aortic infective endocarditis produced by Erysipelothrix rhusiopathiae: case report and review of the literature. The Journal of Heart Valve Disease, 14(3): 320-324, 2005.

Ogawa, Y. et al. The genome of Erysipelothrix rhusiopathiae, the causative agent of swine Erysipelas, reveals new insights into the evolution of Firmicutes and the organism's intracellular adaptations. Journal of Bacteriology, 193(12): 2959-2971, 2011.

Ogawa, Y. et al. Identification of the Chromosomal Region Essential for Serovar-Specific Antigen and Virulence of Serovar 1 and 2 Strains of Erysipelothrix rhusiopathiae. Infection and Immunity, 86(9): e00324-18, 2018.

Olive, D.M.; Bean, P. Principles and Applications of Methods for DNA-Based Typing of Microbial Organisms, Journal of Clinical Microbiology, 37(6): 1661-1669, 1999.

Opriessnig, T. et al. Erysipelothrix rhusiopathiae: genetic characterization of midwest US isolates and live commercial vaccines using pulsed-field gel electrophoresis. Journal of Veterinary Diagnostic Investigation, 16(2): 101-107, 2004.

Opriessnig, T.; Bender, J.S.; Halbur, P.G. Development and Validation of an Immunohistochemical Method for Rapid Diagnosis of Swine Erysipelas in Formalin-Fixed, Paraffin-Embedded Tissue Samples. Journal of Veterinary Diagnostic Investigation, 22(1): 86-90, 2010.

Opriessnig, T.; Coutinho, T.A. Erysipelas. In: Zimmerman, J.J., Karriker, L.A., Ramirez, A.; Schwartz, K.; Stevenson, G.W.; Zhang, J. Diseases of swine. 11th ed. Hoboken, N. J: Wiley Blackwell, 2019. p.835-843.

Opriessnig, T.; Forde, T.; Shimoji, Y. Erysipelothrix Spp.: Past, Present, and Future Directions in Vaccine Research. Frontiers in Veterinary Science, 7:1-18, 2020.

Pal, N.; Bender, J.S.; Opriessnig, T. Rapid detection and differentiation of Erysipelothrix spp. by a novel multiplex real-time PCR assay. Journal of Applied Microbiology, 108(3): 1083-1093, 2009.

Pasteur, L.; Dumas, M. Sur le rouget ou mal rouge des porcs: Extrait d’une lettre Comptes Rendus Hebdomadaires des Séances de l’Academie des Sciences, 95: 1120-1121, 1882.

Pereira, R.P. et al. Anatomopathological aspects and the use of immunohistochemistry in slaughter pigs with cutaneous lesions of erysipelas, Pesquisa Veterinária Brasileira, Pesquisa Veterinária Brasileira, 42: e0997, 2022.

Pescador, C.A. et al. Lesões de pele causadas por Erysipelothrix rhusiopathiae em um feto suíno abortado. Ciência Rural, 37(5): 1475-1479, 2007.

Pomaranski, E.K. et al. Characterization of spaC-type Erysipelothrix sp. isolates causing systemic disease in ornamental fish. Journal of Fish Disease, 41(1): 49–60, 2018.

Pomorska-Mól, M. et al. Effect of age and maternally-derived antibody status on humoral and cellular immune responses to vaccination of pigs against Erysipelothrix rhusiopathiae. The Veterinary Journal, 194(1): 128-130, 2012.

Principe, L. et al. Erysipelothrix rhusiopathiae bacteremia without endocarditis: rapid identification from positive blood culture by MALDI-TOF mass spectrometry. A case report and literature review. Infectious Disease Reports, 8(1): 6368, 2016.

Radostitis, O.M. et al. Veterinary medicine. 8th ed. London: Baillière Tindall, 2003. p.1763.

Ramirez, A. Diferencial Diagnosis of Disease. In: Zimmerman, J. J.; Karriker, L.A.; Ramirez, A.; Shwartz, K.; Stevenson, G.W.; Zhang, J. Disease of swine. 11th Hobokon, NJ: Wiley Blackwell, 2019. p.59-74.

Reboli, A.C.; Farrar, W.E. Erysipelothrix rhusiopathiae: An Occupational Pathogen, Clinical Microbiology Reviews, 2(4): 354-359, 1989.

Reboli, A.C.; Farrar, W.E. The genus Erysipelothrix. In: Balows, A.; Truper, H.G.; Dworkin, M.; Harder, W.; Schleifer, K. The Prokaryotes: A Handbook on the Biology of Bacteria: Ecophysiology, Isolation, Identification, Applications, 2nd ed. New York: Springer, 1992. p.1629-1642.

Reis, T.F.M. et al. First Report of Genetic Variability of Erysipelothrix sp. Strain 2 in Turkeys Associated to Vero Cells Morphometric Alteration. Pathogens, 10(2):1-14, 2021.

Rocha, M.P.; Fontoura, P.R.S.; Azevedo, S.N.B.; Fontoura, A.M.V. Erysipelothrix endocarditis with previous cutaneous lesion: Report of a case and review of the literature. Revista do Instituto de Medicina Tropical de São Paulo, 31(4): 286-289, 1989.

Rosenbach, F.J. Experimentelle morphologische und klinische Studie über die krankheitserregenden Mikroorganismen des Schweinerotlaufs, des Erysipeloids und der Mäusesepsis. Zeitschrift für Hygiene und Infektionskrankheiten, 63(1): 343-369, 1909.

Saldaña, Z. et al. Synergistic role of curli and cellulose in cell adherence and biofilm formation of attaching and effacing Escherichia coli and identification of Fis as a negative regulator of curli. Environmental Microbiology, 11(4): 992-1006, 2009.

Schauer, R. Sialic acids and their role as biological masks, Trends in Biochemical Sciences, 10 (9): 357-360, 1985.

Schulz, L.C. et al. Experimental erysipelas in different species as a model for systemic connective tissue disease. II. The chronic phase with special reference to polyarthritis (author's transl). Beiträge zur Pathologie, 154 (1): 27-51, 1975.

Schulz, L.C. et al. The pathogenetic significance of the acute phase of erysipelas for the manifestation of chronic changes in organs. Comparative studies in swine, mice and rats. Journal of Veterinary Medicine, 23(8): 617-37, 1976.

Shen, H.G.; Bender, J.S.; Opriessnig, T. Identification of surface protective antigen (spa) types in Erysipelothrix reference strains and diagnostic samples by spa multiplex real-time and conventional PCR assays. Journal of Applied Microbiology, 109(4): 1227-1233, 2010.

Shimoji, Y. et al. Construction and Vaccine Potential of Acapsular Mutants of Erysipelothrix rhusiopathiae: Use of Excision of Tn916 to inactivate a target gene. Infection and Immunity, 66(7): 3250-3254, 1998.

Shimoji, Y. Pathogenicity of Erysipleothrix rhusiopathiae: virulence factors and protective immunity. Microbes and Infection, 2(8): 965-972, 2000.

Shimoji, Y. et al. Adhesive Surface Proteins of Erysipelothrix rhusiopathiae Bind to Polystyrene, Fibronectin, and Type I and IV Collagens. Journal of Bacteriology, 185(9): 2739-2748, 2003.

Shimoji, Y. et al. Wild boars: A potential source of Erysipelothrix rhusiopathiae infection Japan. Microbiology and Immunology, 63 (11): 465-468, 2019.

Shiraiwa, K. et al. Identification of serovar 1a, 1b, 2, and 5 strains of Erysipelothrix rhusiopathiae by a conventional gel-based PCR. Veterinary Microbiology, 225: 101-104, 2018.

Shuman, R.D.; Wellman, G. Status of the species name Erysipelothrix rhusiopathiae with request for an opinion. International Journal of Systematic Bacteriology, 16 (2): 195-196, 1966.

Stephenson, E.H.; Berman, D.T. Isolation of Erysipelothrix rhusiopathiae from tonsils of apparently normal swine by two methods. American Journal of Veterinary Research, 39(1): 187–188, 1978.

Takahashi, T. et al. Cross protection in mice and swine immunized with live erysipelas vaccine to challenge exposure with strains of Erysipelothrix rhusiopathiae of various serotypes. American Journal of Veterinary Research, 45(10): 2115-2118, 1984a

Takahashi, T. et al. Antibiotic Resistance of Erysipelothrix rhusiopathiae Isolated from Pigs with Chronic Swine Erysipelas. Antimicrobial Agents and Chemotherapy, 25(3): 385-386, 1984b.

Takahashi, T. et al. Serotype, Antimicrobial Susceptibility, and Pathogenicity of Erysipelothrix rhusiopathiae Isolates from Tonsils of Apparently Healthy Slaughter Pigs. Journal of Clinical Microbiology, 25(3): 536-539, 1987.

Takahashi, T. et al. DNA Relatedness among Erysipelothrix rhusiopathiae Strains Representing All Twenty-Three Serovars and Erysipelothrix tonsillarum. International Journal of Systematic Bacteriology, 42(3): 469-473, 1992.

Takahashi, T. et al. A taxonomic study on erysipelothrix by DNA-DNA hybridization experiments with numerous strains isolated from extensive origins. Microbiology and Immunology, 52 (10): 469-478, 2008.

Takeshi, K. et al. Direct and Rapid Detection by PCR of Erysipelothrix sp DNAs Prepared from Bacterial Strains and Animal Tissues. Journal of Clinical Microbiology, 37(12): 4093-4098, 1999.

Tan, E.M. et al. Erysipelothrix rhusiopathiae bloodstream infection–A 22?year experience at Mayo Clinic, Minnesota Zoonoses and Public Health, 64 (7): e65-e72, 2017.

Tang, H.B. et al. Complete genome sequence of Erysipelothrix rhusiopathiae strain GXBY-1 isolated from acute swine erysipelas outbreaks in south China. Genomics Data, 8: 70-71, 2016.

To, H.; Nagai, S. Genetic and antigenic diversity of the surface protective antigen proteins of Erysipelothrix rhusiopathiae. Clinical and Vaccine Immunology, 14(7): 813-820, 2007.

To, H. et al. Characterization of Erysipelothrix rhusiopathiae strains isolated from recent swine erysipelas outbreaks in Japan. Journal of Veterinary Medical Science, 74 (7): 949?953, 2012.

Verbarg, S. et al. Erysipelothrix inopinata sp. Nov., isolated in the course of sterile filtration of vegetable peptone broth and description of Eysipelotrichaceae fam. Nov. International Journal of Systematic Evolutionary Microbiology, 54: 221-225, 2004.

Wabacha, J.K. et al. An outbreak of urticarial form of swine erysipelas in a medium-scale piggery in Kiambu District, Kenya. South African Veterinary Association, 69(2): 61-63, 1998.

Wang, Q.; Chang, B.K.; Rileu, T.V. Erysipelothrix rhusiopathiae. Veterinary Microbiology, 140 (3-4): 405-417, 2010.

Wood, R.L. Survival of Erysipelothrix rhusiopathiae in soil under various environmental conditions. The Cornell Veterinarian, 63 (3): 390-410, 1973.

Wood, R.L.; Harrington, R. Serotypes of Erysipelothrix rhusiopathiae isolated from swine and from soil and manure of swine pens in the United States. American Journal of Veterinary, Research, 39(11): 1833-1840, 1978.

Wood, R.L. Swine erysipelas-a review of prevalence and research. Journal of the American Veterinary Medical Association, 184 (8): 944-949, 1984.

Wood, R.L. et al. Diseases of swine. 7th ed. Ames: Iowa State University Press, 1992. p.475-486.

Wood, R.L. Erisipelas. In: Straw B.E.; D’Allaire, S.; Mengeling, W.L.; Taylor, D.J. Diseases of swine. 8th ed. Oxford: Blackwell Science, 1999. p.419-430.

Wood, R.L.; Henderson, L.M.; Rapp-Gabrielson, V. Erisipelas. In: Straw, B.E.; Zimmerman, J.J.; D'Allaire, S.; Taylor, D.J. Disease of swine. 9th ed. Ames: Blackwell Publishing, 2006. p. 629-68.

Woodbine, M. Erysipelothrix rhusiopathiae. Bacteriology and Chemotherapy. Bacteriological Reviews, 14(2): 161-178, 1950.

Wu, C. et al. Characterization of Erysipelothrix rhusiopathiae isolates from diseased pigs in 15 Chinese provinces from 2012 to 2018. Microorganisms, 9(12): 2615, 2021.

Xu, C.W. et al. First Report of Macrolide Resistance Gene erm (T) Harbored by a Novel Small Plasmid from Erysipelothrix rhusiopathiae. Antimicrobial Agents and Chemotherapy, 59(4): 2462-2465, 2015.

Yamazaki, Y. A Multiplex Polymerase Chain Reaction for Discriminating Erysipelothrix rhusiopathiae from Erysipelothrix tonsillarium. Journal of Veterinary Diagnostic Investigation, 18(4): 384-387, 2006.

Zhang, A. et al. Presence and new genetic environment of pleuromutilin-lincosamide-streptogramin A resistance gene lsa(E) in Erysipelothrix rhusiopathiae of swine origin. Veterinary Microbiology, 177(1-2): 162-167, 2015.

Downloads

Publicado

28-12-2023

Como Citar

Barbosa, C. N. (2023). Erisipela suína: uma revisão. Medicina Veterinária, 17(4), 277–291. https://doi.org/10.26605/medvet-v17n4-5563

Edição

Seção

Produção Animal

Artigos mais lidos pelo mesmo(s) autor(es)